Neurological

Pinealon

Research Reagent · Laboratory Use Only

Quick Answer

What is Pinealon and how is it different from Epitalon?

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) from the Khavinson short peptide bioregulator family, investigated for neuroprotection and circadian rhythm regulation. Unlike Epitalon (a tetrapeptide focused on telomerase activation), Pinealon targets neuronal gene expression in pineal and hypothalamic tissue.

PMID21161680↗DOI10.1007/s10517-010-1066-1↗⟳ Reconstitution Calculator
Scientific AbstractPMID 21161680 · 2010

Pinealon is a synthetic short peptide (Glu-Asp-Arg) developed in the Russian peptide bioregulator research tradition (Khavinson and colleagues, St. Petersburg Institute of Bioregulation and Gerontology). Research suggests effects on neuronal gene expression, regulation of circadian rhythm-associated pathways, and neuroprotection in age-related cognitive decline models.

Mechanistic studies focus on epigenetic modulation and direct interaction with DNA in pineal and hypothalamic neurons. Pinealon is investigated alongside other Khavinson bioregulators including Epitalon and Cortexin.

Source:10.1007/s10517-010-1066-1
Mechanistic Research SummaryCurated from PubMed

This data is for laboratory research purposes only. Not for human or animal consumption.

What is Pinealon?

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) belonging to the Khavinson short peptide bioregulator family investigated for effects on circadian regulation, neuroprotection, and age-related cognitive decline.

Mechanism of Action

Khavinson-family peptides are hypothesized to act via direct DNA interaction in cell nuclei, modulating gene expression in tissue-specific patterns. Pinealon is studied for activity in pineal gland and hypothalamic neurons with downstream effects on circadian rhythm pathways.

Observed Laboratory Results

  • Neuroprotection in age-related cognitive decline models
  • Circadian rhythm pathway modulation in pineal and hypothalamic tissue
  • Gene expression effects in neuronal cell populations
  • Bioregulator family member alongside Epitalon and Cortexin
Clinical Research ParametersHuman Study Registry

No registered clinical trials or indexed human study data currently available for Pinealon via ClinicalTrials.gov or PubMed. This compound may be at preclinical or early research stages.

Search ClinicalTrials.gov ↗Search PubMed ↗
Research Compliance Notice

All data presented on this page is for laboratory research purposes only. Pinealon is referenced here as a research reagent. This page does not constitute medical advice, clinical guidance, or endorsement of any compound for human or animal use. All referenced studies are available via PubMed (PMID: 21161680) and the DOI-linked journal publication. Researchers must consult applicable institutional and regulatory frameworks before conducting any protocols.

Related Compounds

Other Neurological Research Compounds

Semax
Alzheimer's disease, first described over a century ago, is currently among the most commo…
→
Selank
BACKGROUND: Primary Sjögren's disease (SjD) is a chronic autoimmune disease that predomina…
→
Cerebrolysin
Previous studies from our laboratory show that intraperitoneal injections of 1-metyl-4-phe…
→
Dihexa
BACKGROUND: Huntington's disease (HD) is a neurodegenerative disorder characterized by mot…
→
View all Neurological compounds →