This data is for laboratory research purposes only. Not for human or animal consumption.
What is AOD-9604?
AOD-9604 is a synthetic peptide analog (<2 kDa) classified as a prohibited substance by the World Anti-Doping Agency (WADA) due to its performance-enhancing properties. It is routinely monitored in sports drug testing protocols through advanced mass spectrometry methods.
Mechanism of Action
AOD-9604 functions as a growth hormone secretagogue that modulates endocrine signaling pathways. The peptide is designed to stimulate selective biological responses associated with growth hormone-related pathways while maintaining a low molecular weight profile, making it a target for detection in anti-doping analyses.
Observed Laboratory Results
- Detection Sensitivity: Limits of detection achieved between 50–500 pg/mL, exceeding WADA's minimum required performance level (MRPL) of 2 ng/mL
- Analytical Linearity: Method demonstrated linear response across the working range of 0–10 ng/mL with imprecision <20%, meeting precision standards for quantitative analysis
- Urine Stability: AOD-9604 remained stable in urine samples stored at −20°C, establishing the appropriate storage temperature for sports drug testing protocols and forensic analysis
Testing Method Context
The liquid chromatography–ion-mobility time-of-flight mass spectrometry (LC-IM-TOF-MS) platform enables simultaneous detection of multiple prohibited peptides including GHRP-2, GHRP-6, LHRH, and related growth hormone-releasing peptides (GHRPs), with proof-of-concept validation through elimination study analysis in human urine samples.