This data is for laboratory research purposes only. Not for human or animal consumption.
What is SNAP-8?
SNAP-8 (Acetyl Octapeptide-3) is a cosmetic peptide designed to topically reduce expression wrinkles through a mechanism analogous to — but molecularly distinct from — botulinum toxin.
Mechanism of Action
SNAP-8 is a fragment of SNAP-25, a protein essential for the SNARE complex that controls neurotransmitter vesicle fusion at neuromuscular junctions. By competing with native SNAP-25, SNAP-8 destabilizes SNARE assembly and reduces acetylcholine release at facial muscle endplates.
Observed Laboratory Results
- Reduction of muscle contraction at facial expression sites in topical formulations
- Wrinkle depth reduction measured by skin profilometry in human volunteer studies
- No systemic absorption with topical application
- Slower onset and milder effect than injectable botulinum products